Article

Rab11-FIP1C is dispensable for HIV-1 replication in primary CD4 <sup>+</sup> T cells but its role is cell-type-dependent in immortalized human T-cell lines

2022-06-05

Abstract excerpt

The HIV-1 envelope glycoprotein (Env) contains a long cytoplasmic tail harboring highly conserved motifs that direct Env trafficking and incorporation into virions and promote efficient virus spread. The cellular trafficking factor Rab11a family interacting protein 1C (FIP1C) has been implicated in the directed trafficking of Env to sites of viral assembly. In this study, we confirm that siRNA-mediated depletion o...

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Literature Corpus work: 75cb39e3-9e24-58a0-b067-5b1f2c9804c6
DOI: 10.1101/2022.06.03.494784

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Rab11-FIP1C is dispensable for HIV-1 replication in primary CD4 <sup>+</sup> T cells but its role is cell-type-dependent in immortalized human T-cell linesDOI 10.1101/2022.06.03.494784Read

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