Article

Identification of BLM’s Aggregation-Prone Nature and Its Similarity to Intrinsically Disordered Proteins: An In-silico Study

2024-07-19

Abstract excerpt

BLM helicase is a member of the RecQ family of DNA helicases, enzymes that play a critical role in maintaining genome stability. The BLM protein is named after Bloom syndrome (BS), a rare genetic disorder caused by mutations in the helicase domain of BLM gene. BLM role has mostly been studied in DNA repair, replication, and recombination; however, a recent study has highlighted the RNA binding capability of the BL...

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Literature Corpus work: 75c7b8f0-da2b-5d0e-86a1-6dbb68bb7d07
DOI: 10.1101/2024.07.16.603833

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