Article

MTHFD1 Regulates the NADPH Redox Homeostasis in MYCN-amplified Neuroblastoma

2023-08-17

Abstract excerpt

<title>Abstract</title> <p>MYCN amplification is an independent poor prognostic factor in patients with high-risk neuroblastoma (NB). Further exploring the molecular regulatory mechanisms in MYCN-amplified NB will help to develop novel therapy targets. In this study, methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) was identified as the differentially expressed gene (DEG) highly expressed in MYCN-amplified NB,...

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Literature Corpus work: 8c6ee024-133d-5c38-9de5-f8bee671cba5
DOI: 10.21203/rs.3.rs-3179633/v1

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