Article

The striatum is an early, accurate indicator of amyloid burden using [<sup>11</sup>C]PiB in Down syndrome: comparison of two radiotracers

2024-12-06

Abstract excerpt

<h4>INTRODUCTION</h4> Adults with Down syndrome demonstrate striatum-first amyloid accumulation with [ 11 C]PiB PET imaging, which has not been replicated with [ 18 F]florbetapir (FBP). Early striatal accumulation has not been temporally quantified with respect to global cortical measures. <h4>METHODS</h4> Longitudinal PiB (n=175 participants) and FBP (n=92 participants) data from the Alzheimer Biomarkers Consorti...

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Literature Corpus work: 7593a671-6ffa-540f-bdfa-a1312cb6ff36
DOI: 10.1101/2024.12.04.24318526

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