Variation in infant subcortical brain development from 6 to 12 months in Down syndrome

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Down syndrome (DS), arising from Trisomy 21, is the most common genetic condition associated with intellectual disability. While smaller total brain volumes have been consistently observed in DS, no longitudinal neuroimaging studies have examined volumetric brain development in DS during infancy, a period of rapid neural growth when interventions may have the greatest impa...

Topics

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• Child Development
• Cognition
• Connectome
• Diffusion Magnetic Resonance Imaging
• DNA Methylation
• Down syndrome and intellectual disability research
• Fetal and Pediatric Neurological Disorders
• Prenatal Screening and Diagnostics

Identifiers and source

Literature Corpus work

51a146a2-434a-5a89-b20b-b774cde5a0d7

DOI

10.64898/2026.06.16.732759