A systematic review of gene editing clinical trials

Abstract excerpt

Gene editing technologies such as zinc finger nuclease (ZFN), transcription activator-like effector nuclease (TALEN), and clustered regularly interspaced short palindromic repeats (CRISPR) have revolutionized genetic engineering and now are being used in clinical gene therapy. We systematically reviewed gene editing clinical trials from ClinicalTrials.gov using a searching strategy that included all different gene...

Topics

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• Biomedical Ethics and Regulation
• CRISPR and Genetic Engineering
• CRISPR-Cas Systems
• Disease Management
• Gene Editing
• Gene Targeting
• Genetic Therapy
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

757f3ec8-012c-5b18-862a-da92635833c3

DOI

10.1101/2022.11.24.22282599