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Comparison of the Feasibility, Efficiency, and Safety of Genome Editing Technologies

26 Sept 2021

Abstract excerpt

Recent advances in programmable nucleases including meganucleases (MNs), zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats-Cas (CRISPR-Cas) have propelled genome editing from explorative research to clinical and industrial settings. Each technology, however, features distinct modes of action that unevenly impact...

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PMID: 34638696
DOI: 10.3390/ijms221910355

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