Article

Lithium Response in Bipolar Disorder is Associated with Focal Adhesion and PI3K-Akt Networks: A Multi-omics Replication Study

2023-10-03

Abstract excerpt

<title>Abstract</title> <p>Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study of the Pharmacogenomics of Bipolar Disorder (PGBD) sample combining transcriptomic and genomic data, we found that focal adhesion, the extracellular matrix (ECM), and PI3K-Akt sig...

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Literature Corpus work: 757deeb3-1329-5d1f-8b34-e2ef0b325a97
DOI: 10.21203/rs.3.rs-3258813/v1

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