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Article

Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis

29 Mar 2023

Abstract excerpt

Abstract Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this study is to identify functional genes and pathways that distinguish BD Li responders (LR) from BD Li non-responders (NR). An initial Pharmacogenomics of Bipolar Disorder study (PGBD) GWAS of lithium response did not provide any...

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PMID: 36991131
DOI: 10.1038/s41380-022-01909-9

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