Article

Combined analysis of somatic mutations and gene expression reveals nuclear speckles-associated enhanced stemness in gingivobuccal carcinoma under DNA damage response

2024-11-18

Abstract excerpt

<h4>ABSTRACT</h4> Smokeless tobacco chewing habits in India lead to a high prevalence of Gingivobuccal oral squamous cell carcinoma (OSCC-GB). Cancer stem cells (CSCs) are a sub-population of cancer cells within a tumor with stem-like properties and are believed to contribute to tumor initiation, progression, increased resistance to drug therapy, and promote post-therapeutic cancer relapse. An RNA-seq data-based...

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Literature Corpus work: 757d1f46-3e49-5025-a65c-328a731dcbaa
DOI: 10.1101/2024.11.16.623931

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