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The combination of transcriptome and Mendelian randomization reveals clinical and immuno-functional biomarkers of alternative splicing regulation associated with planar cell polarity signaling pathways in pan-cancer

2024-03-28

Abstract excerpt

<h4>Background: </h4> The intricate interplay between alternative splicing (AS) events and the planar cell polarity (PCP) signaling pathway is known to play a crucial role in cancer initiation and progression. Understanding the prognostic implications and immunological features of PCP-related AS events can unveil novel biological markers and potential targets for immunotherapy. Methods We sourced genes associated...

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Literature Corpus work
7532ea96-e59d-5bc3-b086-d1230b71941a
DOI
10.21203/rs.3.rs-4115366/v1
Open publication

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The combination of transcriptome and Mendelian randomization reveals clinical and immuno-functional biomarkers of alternative splicing regulation associated with planar cell polarity signaling pathways in pan-cancerDOI 10.21203/rs.3.rs-4115366/v1
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