Article
Developmental co-emergence of cardiac and gut tissues modeled by human iPSC-derived organoids
2020-05-01
Abstract excerpt
During embryogenesis, paracrine signaling between tissues in close proximity contributes to the determination of their respective cell fate(s) and development into functional organs. Organoids are in vitro models that mimic organ formation and cellular heterogeneity, but lack the paracrine input of surrounding tissues. Here, we describe a human multilineage iPSC-derived organoid that recapitulates cooperative car...
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Identifiers and source
- Literature Corpus work
- 0237728a-5342-5323-ae70-003c6c6eff68
- DOI
- 10.1101/2020.04.30.071472