Article
A patterned human heart tube organoid model generated by pluripotent stem cell self-assembly
2022-12-19
Abstract excerpt
Human pluripotent stem cells can recapitulate significant features of mammalian organ development in vitro , including key aspects of heart development. We hypothesized that the organoids thus created can be made substantially more relevant by mimicking aspects of in utero gestation, leading to higher physiological and anatomical resemblance to their in vivo counterparts. Here, we report steps towards generatin...
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Identifiers and source
- Literature Corpus work
- 2aace74c-e4fb-5dfc-aec9-f542e0b3c49e
- DOI
- 10.1101/2022.12.16.519611