Article

Persistently Elevated Donor-Derived Cell-Free DNA After Kidney Transplantation in Atypical Hemolytic Uremic Syndrome: A Preliminary Observational Study

2026-07-27

Abstract excerpt

Donor-derived cell-free DNA (dd-cfDNA) is an emerging non-invasive biomarker of kidney allograft injury. Elevated dd-cfDNA has been associated with acute rejection, particularly antibody-mediated rejection; however, dd-cfDNA reflects graft-derived tissue injury rather than a specific alloimmune mechanism. Its interpretation may therefore be challenging in conditions characterized by endothelial and microvascular i...

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Literature Corpus work: 74e9cfa9-b5d4-53e6-bf34-062ad0804c99
DOI: 10.20944/preprints202607.1886.v1

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