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Associations between donor-derived cell-free DNA dynamics and clinical outcomes after kidney allograft rejection: A prospective, multicenter study

23 Jul 2025

Abstract excerpt

Active rejection (AR) remains a major risk factor for graft dysfunction and loss. Donor-derived cell-free DNA (dd-cfDNA) is a dynamic, noninvasive biomarker for AR. We hypothesized that dd-cfDNA monitoring post-rejection may enable physicians to stratify patients into those with more and less favorable prognoses. This prospective multi-center study of kidney transplant recipients (KTR) with biopsy proven AR...

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Share to Organ Donation and Transplantation
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PMID: 40712889
DOI: 10.1016/j.ajt.2025.07.2470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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