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Article

Analysis of the primary factors influencing donor derived cell-free DNA testing in kidney transplantation.

Frontiers in immunology - 1 Jan 2024

Cao Changling, Yuan Li, Wang Yinfeng, Liu Haitao, Cuello Garcia Haider, Huang Huiqiang, Tan Weiqiang, Zhou Yang, Shi Haifeng, Jiang Tingya

Abstract excerpt

The donor-derived cell-free DNA (ddcfDNA) is found in the plasma and urine of kidney transplant recipients and displays notable potential in diagnosing rejection, specifically antibody-mediated rejection (ABMR). Nonetheless, the quantitative methods of ddcfDNA lacking standardization and diverse detection techniques can impact the test outcomes. Besides, both the fraction and absolute values of ddcfDNA have been...

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Identifiers

PMID: 39308855
DOI: 10.3389/fimmu.2024.1435578
PMCID: PMC11412870

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