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Elevation of Donor-derived Cell-free DNA Before Biopsy-proven Rejection in Kidney Transplant

10 Apr 2024

Abstract excerpt

BACKGROUND: Standard-of-care biomarkers for renal allograft rejection are lagging indicators, signaling existing organ injury. This precludes early intervention, when immunological cascades leading to rejection are most susceptible. Donor-derived cell-free DNA (dd-cfDNA) shows promise as an early indicator of rejection, allowing earlier and possibly more effective treatment. This analysis was designed to assess...

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PMID: 38595232
DOI: 10.1097/tp.0000000000005007

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