Article

Accounting for Spatial Correlation in Graphical Analysis of Spatial Transcriptomics Data

2025-07-27

Abstract excerpt

Co-expression analysis is key for understanding disease mechanisms and gene regulatory and functional relationships. In spatial transcriptomics, estimating gene correlation is challenging due to correlation among cells, which can lead to spurious associations that obscure true biological associations. To address this, we propose SpaceDecorr, a method that adjusts gene expression for technical artifacts and spatial...

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Literature Corpus work: 74b2ec4b-c055-5698-8517-5b8b0f34c9ae
DOI: 10.1101/2025.07.23.666450

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