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A long intergenic non-coding RNA regulates nuclear localisation of DNA methyl transferase-1

2020-03-12

Abstract excerpt

<h4>ABSTRACT</h4> DNA methyl-transferase-1 or DNMT1 maintains DNA methylation in the genome and is important for regulating gene expression in cells. Aberrant changes in DNMT1 activity are observed in many diseases. Therefore, understanding the mechanisms behind alteration of DNMT1 activity is important. Here, we show that CCDC26 , a nuclear long non-coding RNA frequently mutated in myeloid leukaemia, directly i...

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Literature Corpus work
74a0c20a-bcb9-53e3-9e67-b7cc26168a11
DOI
10.1101/2020.03.11.985705
Open publication

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A long intergenic non-coding RNA regulates nuclear localisation of DNA methyl transferase-1DOI 10.1101/2020.03.11.985705
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