Article

PRMT activity promotes global 3’ UTR shortening in proliferating cells

2025-03-10

Abstract excerpt

<h4>ABSTRACT</h4> Protein methyltransferase (PRMT)-catalysed arginine methylation is a widespread post-translational modification that regulates numerous RNA-binding proteins and frequently becomes dysregulated in cancer. While PRMT inhibitors have shown promise as an anti-cancer strategy, greater understanding of the downstream pathways linking arginine methylation to tumour-promoting phenotypes is needed to imp...

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Literature Corpus work: 3c240fc2-92e2-5c69-998b-f3efca98a90d
DOI: 10.1101/2025.03.06.641848

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