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Rv0783c of <i>Mycobacterium tuberculosis</i> acts as a proton-motive force dependent multidrug efflux transporter involved in the efflux of structurally unrelated antibiotics and enhancing biofilm formation

2026-04-01

Abstract excerpt

Despite multiple treatment strategies and extensive research on resistance mechanisms, tuberculosis (TB) remains a major global health threat, largely because of the rise of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB. Among various mechanisms complicating the situation, active antibiotic export via efflux pumps is particularly significant, yet largely unexplored. Mycobacterium sp. encodes n...

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Literature Corpus work
7499b548-fc45-5a89-a77e-78812c0b2e92
DOI
10.64898/2026.04.01.715825
Open publication

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Rv0783c of <i>Mycobacterium tuberculosis</i> acts as a proton-motive force dependent multidrug efflux transporter involved in the efflux of structurally unrelated antibiotics and enhancing biofilm formationDOI 10.64898/2026.04.01.715825
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