Article

EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis

2024-03-10

Abstract excerpt

Idiopathic scoliosis (IS) is the most common form of spinal deformity with unclear pathogenesis. In this study, we firstly reanalyzed the loci associated with IS, drawing upon previous studies. Subsequently, we mapped these loci to candidate genes using either location-based or function-based strategies. To further substantiate our findings, we verified the enrichment of variants within these candidate genes acros...

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Identifiers and source

Literature Corpus work: 5738762b-d27a-5493-aa84-fe2a8ea90019
DOI: 10.1101/2024.03.04.583361

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