Article

Characterization and validation of long-term cultured TERT-immortalized human Wharton’s jelly–derived mesenchymal stromal cells

2025-12-18

Abstract excerpt

<title>Abstract</title> <p>Mesenchymal stromal cells (MSCs) have demonstrated efficacy and feasibility in numerous preclinical and clinical studies. However, their application is limited at early passages owing to replicative senescence. This study investigated whether MSCs immortalized via human telomerase reverse transcriptase (TERT) overexpression (TERT-MSCs) maintain their characteristics and efficacy after e...

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Literature Corpus work: 742f390d-865e-5fe3-9f4a-bba976d00c86
DOI: 10.21203/rs.3.rs-8322013/v1

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