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Article

How to track cellular aging of mesenchymal stromal cells?

8 Apr 2010

Abstract excerpt

Mesenchymal stromal cells (MSC) are currently tested in a large number of clinical trials and raise high hope in regenerative medicine. These cells have to be expanded in vitro before transplantation and several studies demonstrated that long-term culture evokes continuous changes in MSC: proliferation rate decays, the cell size increases, differentiation potential is affected, chromosomal instabilities may arise...

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PMID: 20453259
DOI: 10.18632/aging.100136

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