Article

Motor Learning Promotes Remyelination via New and Surviving Oligodendrocytes

2020-01-29

Abstract excerpt

Oligodendrocyte loss in neurological disease leaves axons vulnerable to damage and degeneration, and activity-dependent myelination may represent an endogenous mechanism to improve remyelination following injury. Here, we report that while learning a forelimb reach task transiently suppresses oligodendrogenesis, it subsequently increases OPC differentiation, oligodendrocyte generation, and retraction of pre-existi...

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Literature Corpus work: 741a8611-64e8-55a3-b292-f83c1cf73a8c
DOI: 10.1101/2020.01.28.923656

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