neoANT-HILL: an integrated tool for identification of potential neoantigens

Abstract excerpt

BACKGROUND: Cancer neoantigens have attracted great interest in immunotherapy due to their capacity to elicit antitumoral responses. These molecules arise from somatic mutations in cancer cells, resulting in alterations on the original protein. Neoantigens identification remains a challenging task due largely to a high rate of false-positives. RESULTS: We have developed an efficient and automated pipeline for the...

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