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Article

GFAP splice variants fine-tune glioma cell invasion and tumour dynamics by modulating migration persistence

2021-08-19

Abstract excerpt

Glioma is the most common form of malignant primary brain tumours in adults. Their highly invasive nature makes the disease incurable to date, emphasizing the importance of better understanding the mechanisms driving glioma invasion. Glial fibrillary acidic protein (GFAP) is an intermediate filament protein that is characteristic for astrocyte- and neural stem cell-derived gliomas. Glioma malignancy is associated...

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Literature Corpus work
73b69335-a9f8-59a5-ac4b-34ca2d78cc8a
DOI
10.1101/2021.08.19.456978
Open publication

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