Article

Ginkgolic acid attenuates <i>echinococcus granulosus</i> infection-induced hepatic fibrosis by inhibiting Smad4 SUMOylation

2025-08-24

Abstract excerpt

<h4>Background</h4> The SUMOylation modification is closely linked to the progression of fibrotic diseases, yet its role in hepatic fibrosis associated with cystic echinococcosis (CE) remains unclear. This study aimed to investigate the function of SUMOylation in CE-related hepatic fibrosis and evaluate the anti-fibrotic effects and mechanisms of ginkgolic acid (GA) via regulation of the SUMOylation pathway. <h4>...

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Literature Corpus work: 7364e9db-858a-59ac-b1a3-46ee16ce40e1
DOI: 10.1101/2025.08.22.671734

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