Article

Legacy Data Confounds Genomics Studies

2019-05-03

Abstract excerpt

Recent reports have identified differences in the mutational spectra across human populations. While some of these reports have been replicated in other cohorts, most have been reported only in the 1000 Genomes Project (1kGP) data. While investigating an intriguing putative population stratification within the Japanese population, we identified a previously unreported batch effect leading to spurious mutation call...

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Literature Corpus work: 733b4d43-0fc3-5a0e-843d-cd577f870345
DOI: 10.1101/624908

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