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Article

ERα-independent NRF2-mediated immunoregulatory activity of tamoxifen

2024-01-31

Abstract excerpt

<h4>Background: </h4> and Purpose: Sex differences in immune-mediated diseases are linked to the activity of estrogens on innate immunity cells, including macrophages. Tamoxifen (TAM) is a selective estrogen receptor modulator (SERM) used in estrogen receptor-alpha (ERα)-dependent breast cancers and off-target indications such as infections, although the immune activity of TAM and its active metabolite, 4-OH tamox...

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Literature Corpus work
733810da-de1b-53ca-9507-3e27ee96ed04
DOI
10.22541/au.170666818.89952402/v1
Open publication

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ERα-independent NRF2-mediated immunoregulatory activity of tamoxifenDOI 10.22541/au.170666818.89952402/v1
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