Article

Prevention of EloR/KhpA heterodimerization by introduction of site-specific amino acid substitutions renders the essential elongasome protein PBP2b redundant in Streptococcus pneumoniae

2018-10-05

Abstract excerpt

The RNA binding proteins EloR and KhpA are important components of the regulatory network that controls and coordinates cell elongation and division in S. pneumoniae . Loss of either protein reduce cell length, and makes the essential elongasome proteins PBP2b and RodA dispensable. It has been shown previously in formaldehyde crosslinking experiments that EloR co-precipitates with KhpA, indicating that they form...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 73304522-ab96-52da-ba2e-6de4c49c33ad
DOI: 10.1101/435529

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Prevention of EloR/KhpA heterodimerization by introduction of site-specific amino acid substitutions renders the essential elongasome protein PBP2b redundant in Streptococcus pneumoniaeDOI 10.1101/435529Read

Absence of the KhpA and KhpB (JAG/EloR) RNA-binding proteins suppresses the requirement for PBP2b by overproduction of FtsA in Streptococcus pneumoniae D39.Semantic proximity Read

Structure of the large extracellular loop of FtsX and its interaction with the essential peptidoglycan hydrolase PcsB in Streptococcus pneumoniaeSemantic proximity Read

Identification of EloR (Spr1851) as a regulator of cell elongation in Streptococcus pneumoniae.Semantic proximity Read

Structural characterization of the essential cell division protein FtsE and its interaction with FtsX in Streptococcus pneumoniaeSemantic proximity Read

Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniaeSemantic proximity Read

Molecular genetic characterization of bacterial KH-domain proteinsSemantic proximity Read

KH domains with impaired nucleic acid binding as a tool for functional analysis.Semantic proximity Read

Understanding and re-engineering nucleoprotein machines to cure human disease.Semantic proximity Read

Engineered Ubiquitin Variants Mitigate Pathogenic Bacterial Ubiquitin Ligase FunctionSemantic proximity Read

Fine-tuning cellular levels of DprA ensures transformant fitness in the human pathogen Streptococcus pneumoniaeSemantic proximity Read

Essential PcsB putative peptidoglycan hydrolase interacts with the essential FtsX Spn cell division protein in Streptococcus pneumoniae D39Semantic proximity Read

Dual control of host actin polymerization by a Legionella effector pairSemantic proximity Read

Prevention of EloR/KhpA heterodimerization by introduction of site-specific amino acid substitutions renders the essential elongasome protein PBP2b redundant in <i>Streptococcus pneumoniae</i>

Abstract excerpt

Topics

Identifiers and source

Related research