Article

Genotype’s Role in Beta Thalassemia: From DNA to Disease

2026-07-20

Abstract excerpt

<title>Abstract</title> <p>Background: Beta-thalassemia is a common hemoglobinopathy in India with clinical manifestations ranging from severe transfusion-dependent anemia to asymptomatic carrier states. Chronic transfusions and ineffective erythropoiesis lead to iron overload, oxidative stress, and progressive organ damage, including renal dysfunction. <h4>Objective:</h4> To evaluate oxidative stress, renal fun...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8eddf4ae-8f7a-5e2c-9963-64cf06be2149
DOI: 10.21203/rs.3.rs-10389283/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genotype’s Role in Beta Thalassemia: From DNA to DiseaseDOI 10.21203/rs.3.rs-10389283/v1Read

Genotype-Phenotype Correlation of Β-Globin Mutations and Hematological Parameters in Iraqi Β-Thalassemia Patients.Semantic proximity Read

Clinical Laboratory Manifestation and Molecular Diagnosis of β-Thalassemia Patients in Iraq.Semantic proximity Read

Genetic variations and clinical implications of B-thalassemia in Iraqi population.Semantic proximity Read

Clinical experience using peripheral blood parameters to analyse the mutation type of thalassemia carriers in pregnant women.Semantic proximity Read

Mutation Spectrum of β-Thalassemia in Some Ethnic Groups of North Maharashtra, India.Semantic proximity Read

Genetic determinants of phenotype in beta-thalassemia.Semantic proximity Read

Recent progress in laboratory diagnosis of thalassemia and hemoglobinopathy: a study by the Korean Red Blood Cell Disorder Working Party of the Korean Society of HematologySemantic proximity Read

Understanding the Intricacies of Iron Overload Associated With β-Thalassemia: A Comprehensive ReviewSemantic proximity Read

Thalassemia, a human blood disorderSemantic proximity Read

Genotypic and Clinical Analysis of a Thalassemia Major Cohort: An Observational Study.Semantic proximity Read

Burdwan University Thalassemia Severity (BUTS) Scoring System: A numerical Method For Defining the Clinicopathological status of Thalassaemia PatientSemantic proximity Read

Detection of Common Deletion Mutations (− α<sup>3.7</sup>and − α<sup>4.2</sup>kb) in<i>HBA</i>gene and Genotype-Phenotype CorrelationSemantic proximity Read