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Genetic Variants at BCL11A and HBS1L-MYB loci Influence Hb F Levels in Chinese Zhuang β-Thalassemia Intermedia Patients.

Hemoglobin - 1 Nov 2016

Lai Yunli, Chen Yun, Chen Biyan, Zheng Haiyang, Yi Sheng, Li Guojian, Wei Hongwei, He Sheng, Zheng Chenguang

Abstract excerpt

Increased Hb F levels can ameliorate the symptoms of β-thalassemia (β-thal). Due to the genetic heterogenicity of β-thal, the relationship between genetic variants in modifier genes and Hb F level has been studied in different populations. The Chinese Zhuang has the second largest population in China and has 6.78% prevalence of β-thal. However, the effects of these single nucleotide polymorphism (SNP) variants on...

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PMID: 28361591
DOI: 10.1080/03630269.2016.1253586

Genes

MYB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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