Article
No evidence that natural selection has been less effective at removing deleterious mutations in Europeans than in West Africans
2014-02-20
Abstract excerpt
Non-African populations have experienced major bottlenecks in the time since their split from West Africans, which has led to the hypothesis that natural selection to remove weakly deleterious mutations may have been less effective in non-Africans. To directly test this hypothesis, we measure the per-genome accumulation of deleterious mutations across diverse humans. We fail to detect any significant differences,...
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Identifiers and source
- Literature Corpus work
- 72e96835-578a-50d8-823c-bcd93bcdf90e
- DOI
- 10.1101/002865