Article

Systemic and local chronic inflammation and hormone disposition promote a tumor-permissive environment for breast cancer in older women

2024-10-21

Abstract excerpt

Estrogen receptor positive (ER+) breast cancer is the most common subtype of breast cancer and is an age-related disease. The peak incidence of diagnosis occurs around age 70, even though these post-menopausal patients have low circulating levels of estradiol (E2). Despite the hormone sensitivity of age-related tumors, we have a limited understanding of the interplay between systemic and local hormones, chronic in...

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Literature Corpus work: 72c43a59-273e-5901-8c37-be3d0ad6b8c2
DOI: 10.1101/2024.10.18.616978

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