Article

Mammary hydroxylated oestrogen activates the NLRP3 inflammasome in tumor-associated macrophages to promote breast cancer progression and metastasis

2023-09-29

Abstract excerpt

<h4>Background: </h4> An imbalance of oestrogen homeostasis and an inflammatory tumor microenvironment (TME) are vital risk factors for the progression and metastasis of breast cancer. <h4>Methods: </h4> The liquid chromatography-tandem mass spectrometry (LC-MS/MS) quantitative analysis method for oestrogen active substances was used to detect the levels of oestrogen and its metabolites of 238 clinical serum samp...

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Literature Corpus work: b9d04a67-e3c3-590f-bb18-70bfc7a39ac8
DOI: 10.21203/rs.3.rs-3381051/v1

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