Article

Latent HIV Infection of BBB Pericytes Disrupts Gap Junction-Mediated Crosstalk with Endothelial Cells

2026-08-12

Abstract excerpt

<title>Abstract</title> <p>HIV-Associated Neurocognitive Impairments persist, with over 50% of patients experiencing cognitive decline. Blood-brain barrier (BBB) impairment is a consistent feature of this comorbidity, which is remarkable, because BBB endothelial cells are not productively infected by HIV-1. Conversely, pericytes can be productively infected with HIV-1 and are essential for cerebrovascular homeost...

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Literature Corpus work: 72c06b35-726a-5f51-9821-284e982e0051
DOI: 10.21203/rs.3.rs-10321172/v1

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