Article

miR-765 Impairs Pancreatic β-cell Function by Targeting PDX1 in type 2 Diabetes

2020-07-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Type 2 diabetes (T2D) is highly connected with the defect in insulin secretion of pancreatic β-cells, which has been developing into a severe public health problem.<bold>Methods:</bold> Here, we first detected expression of PDX1 and miR-765 in peripheral blood from 40 patients with T2D and 40 healthy volunteers. INS-1E cells (pancreatic β-cell line) were culture...

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Literature Corpus work: 722f21c5-df3e-5278-a9c3-c3eafb0b51a0
DOI: 10.21203/rs.3.rs-44969/v1

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