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Application of microRNAs in diabetes mellitus

29 Apr 2014

Abstract excerpt

MicroRNAs (miRNAs) are small molecules negatively regulating gene expression by diminishing their target mRNAs. Emerging studies have shown that miRNAs play diverse roles in diabetes mellitus. Type 1 diabetes (T1D) and T2D are two major types of diabetes. T1D is characterized by a reduction in insulin release from the pancreatic β-cells, while T2D is caused by islet β-cell dysfunction in response to insulin...

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PMID: 24781254
DOI: 10.1530/joe-13-0544

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