Article

Sex stratified analyses enable new genetic insights into brain imaging phenotypes

2026-04-21

Abstract excerpt

Sex differences are commonly observed in neuroimaging phenotypes and in the risk of brain diseases, yet the underlying genetic mechanisms remain poorly understood. We investigated sex differences in the genetic architecture of 805 neuroimaging phenotypes in 22,950 males and 22,950 females matched for sample size and covariates, and systematically compared sex-stratified with sex-combined genetic analyses. We found...

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Literature Corpus work: 722b2bd0-634d-54e3-bdc8-e98a600520db
DOI: 10.64898/2026.04.21.719541

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