Article

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

2016-06-07

Abstract excerpt

Ultra-rare inherited and de novo disruptive variants in highly constrained (HC) genes are enriched in neurodevelopmental disorders 1–5 . However, their impact on cognition in the general population has not been explored. We hypothesize that disruptive and damaging ultra-rare variants (URVs) in HC genes not only confer risk to neurodevelopmental disorders, but also influence general cognitive abilities measured i...

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Identifiers and source

Literature Corpus work: 72256793-0556-5c4b-ba8d-22ab8234c52f
DOI: 10.1101/050195

Open publication

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