Article
Molecular characterization of endometrial cancer and therapeutic implications.
Current opinion in obstetrics & gynecology - 1 Feb 2017
Uppendahl Locke, Mullany Sally A, Winterhoff Boris
Abstract excerpt
PURPOSE OF REVIEW: This article reviews the emerging comprehensive genomic classification of endometrial carcinoma and discusses the therapeutic implications of these subgroups. RECENT FINDINGS: Comprehensive, multiplatform evaluation of endometrial cancers by the Cancer Genome Atlas stratified the molecular aberrations into four distinct subtypes: POLE mutations, microsatellite instability, copy-number...
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