Article

Impaired Capillary Endothelial Cell Differentiation Contributes to pulmonary hypertension in a dynamic Capillary-Alveoli Micro-physiological System and animal models

2026-02-25

Abstract excerpt

Pulmonary hypertension (PH) is a progressive condition characterized by increased pulmonary arterial pressure. Endothelial cell dysfunction is one important characteristic of PH. Recently, capillary endothelial cells, including aerocytes (aCaps) and general capillary cell (gCaps), have been detected in developing lungs but their role and the regulatory mechanisms underlying PH remain poorly understood. The goal of...

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Literature Corpus work: 71f5790b-8d7f-5ee9-be61-cc28946839dc
DOI: 10.64898/2026.02.21.26346776

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