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Spatial profiling reveals complex inflammatory responses of anti-IL5 treatment with mepolizumab in eosinophilic chronic rhinosinusitis with nasal polyposis

2024-10-22

Abstract excerpt

<h4>Background: </h4> There is limited understanding of the impact of anti-IL5 treatment on nasal polyp tissue biology in chronic rhinosinusitis with nasal polyps (CRSwNP). The aim of this study was to determine the effect of the nasal polyp tissue cellular proteome and transcriptome in response to six months of anti-IL5 treatment with mepolizumab in CRSwNP utilising high-plex spatial profiling. <h4>Methods:</h4>...

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Literature Corpus work
719e9f08-9d60-54c3-a836-b7604cf6efd5
DOI
10.22541/au.172956247.70378401/v1
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Spatial profiling reveals complex inflammatory responses of anti-IL5 treatment with mepolizumab in eosinophilic chronic rhinosinusitis with nasal polyposisDOI 10.22541/au.172956247.70378401/v1
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