Article

Increased epithelial mTORC1 activity in chronic rhinosinusitis with nasal polyps

2023-10-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The airway epithelium plays a central role in the pathogenesis of chronic respiratory diseases such as asthma and chronic rhinosinusitis with nasal polyps (CRSwNP), but the mechanisms by which airway epithelial cells (EpCs) maintain inflammation are poorly understood. <h4>Objective</h4> We hypothesized that transcriptomic assessment of sorted airway EpCs across the spectrum...

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Literature Corpus work: 23203156-f71b-58bb-a3db-0267f2b3616d
DOI: 10.1101/2023.10.13.562288

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