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Article

Transcriptomic Differentiation of Phenotypes in Chronic Rhinosinusitis and Its Implications for Understanding the Underlying Mechanisms.

International journal of molecular sciences - 14 Mar 2023

Urbančič Jure, Košak Soklič Tanja, Demšar Luzar Ajda, Hočevar Boltežar Irena, Korošec Peter, Rijavec Matija

Abstract excerpt

Chronic rhinosinusitis (CRS) is a multifaceted disease with variable clinical courses and outcomes. We aimed to determine CRS-associated nasal-tissue transcriptome in clinically well-characterized and phenotyped individuals, to gain a novel insight into the biological pathways of the disease. RNA-sequencing of tissue samples of patients with CRS with polyps (CRSwNP), without polyps (CRSsNP), and controls were...

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Source

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Identifiers

PMID: 36982612
DOI: 10.3390/ijms24065541
PMCID: PMC10051401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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