Back to search

Article

Transcriptomics unravels molecular changes associated with cilia and COVID-19 in chronic rhinosinusitis with nasal polyps.

2022-09-16

Abstract excerpt

Chronic rhinosinusitis with nasal polyps is a common condition where the pathogenesis is largely unknown. We measured total gene expression in nasal mucosa using RNA sequencing technology. Pathways involving “Ciliated epithelial cells” were the most differentially expressed molecular pathways when polyp mucosa and non-polyp mucosa from the same patient was compared (p = 8.5x10 − 78 ). Natural killer T-cell (NKT) (...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3a92cba2-220b-523e-8548-1124b96a8073
DOI
10.21203/rs.3.rs-1825032/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Transcriptomics unravels molecular changes associated with cilia and COVID-19 in chronic rhinosinusitis with nasal polyps.DOI 10.21203/rs.3.rs-1825032/v1
Transcriptomics unravels molecular changes associated with cilia and COVID-19 in chronic rhinosinusitis with nasal polypsSemantic proximity
Transcriptomic Differentiation of Phenotypes in Chronic Rhinosinusitis and Its Implications for Understanding the Underlying Mechanisms.Semantic proximity
Whole-transcriptome sequencing reveals heightened inflammation and defective host defence responses in chronic rhinosinusitis with nasal polypsSemantic proximity
Single cell transcriptomic analysis reveals transcriptome differences of different cells between eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polypsSemantic proximity
Transcriptome Analysis Reveals Distinct Gene Expression Profiles in Eosinophilic and Noneosinophilic Chronic Rhinosinusitis with Nasal PolypsSemantic proximity
Comparison of Gene Expression between Chronic Rhinosinusitis with Nasal Polyposis and without Nasal PolyposisSemantic proximity
Single-cell RNA sequencing reveals the epithelial cell, fibroblast, and key gene alterations in chronic rhinosinusitis with nasal polypsSemantic proximity
The global transcriptomic signature in sinonasal tissues reveals roles for tissue type and chronic rhinosinusitis disease phenotype.Semantic proximity
Latest advances in chronic rhinosinusitis with nasal polyps endotyping and biomarkers, and their significance for daily practice.Semantic proximity
FCGR3A+CD8+ cytotoxic T effector subset with NK-cell-like features promotes disease progression in eosinophilic chronic rhinosinusitis with nasal polypsSemantic proximity
scRNA-seq reveals persistent aberrant differentiation of nasal epithelium driven by TNFα and TGFβ in post-COVID syndromeSemantic proximity
Identification of differential pathogenic mechanisms between chronic rhinosinusitis with nasal polyps and odontogenic sinusitis using the PrimeView™ Human Gene Expression ArraySemantic proximity
Select a neighboring publication to make it the new centre.