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Article

Ex-vivo models of post-surgical residual disease in human glioblastoma

2024-11-04

Abstract excerpt

Background Glioblastoma is a highly infiltrative, currently incurable brain cancer. To date, translation of novel therapies for glioblastoma from the laboratory into clinical trials has relied heavily on in vitro cell culture and murine (subcutaneous and orthotopic) xenograft models using cells derived from the main bulk of patient tumours. However, it is the residual cells left-behind after surgery that are resp...

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Literature Corpus work
719197ac-33d5-570e-97e1-3508936ad1a9
DOI
10.12688/f1000research.157013.1
Open publication

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