Article

Chronic Delta-9-Tetrahydrocannabinol (THC) Treatment Counteracts SIV-induced Modulation of Proinflammatory microRNA Cargo in Basal-ganglia-derived Extracellular- Vesicles

2022-01-28

Abstract excerpt

<h4>Background: </h4> Early invasion of the central nervous system (CNS) by human immunodeficiency virus (HIV) (1, 2), results in neuroinflammation, potentially through extracellular vesicles (EVs) and their micro RNAs (miRNA) cargoes (3, 4). Although the basal ganglia (BG) is a major target and reservoir of HIV in the CNS (5, 6), whether BG produces EVs and the effect of HIV and/or the phytocannabinoid― delta-9-t...

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Literature Corpus work: 7160d16f-ec19-52cb-868e-96e70a9ab51f
DOI: 10.21203/rs.3.rs-1292643/v1

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