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Cannabidiol modulates expression of type I IFN response genes and HIV infection in macrophages

29 Sept 2022

Abstract excerpt

) is a widely used drug in the United States and the frequency of cannabis use is particularly high among people living with HIV (PLWH). One key component of cannabis, the non-psychotropic (-)-cannabidiol (CBD) exerts a wide variety of biological actions, including anticonvulsive, analgesic, and anti-inflammatory effects. However, the exact mechanism of action through which CBD affects the immune cell signaling...

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PMID: 36248834
DOI: 10.3389/fimmu.2022.926696

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